Amino Acids

アミノ酸
Hydrating (保湿) cosmetic moderate evidence

What It Does

The building blocks of the skin's natural moisturizing factor (NMF). Gentle, effective hydrators that strengthen the moisture barrier.

Amino acids are the building blocks of proteins like collagen, keratin, and elastin. They are also major components of the skin natural moisturizing factors (NMF), a complex of water-soluble compounds that keep the stratum corneum hydrated. Common amino acids in skincare include glycine, alanine, serine, arginine, and proline.

When applied topically, amino acids help replenish the NMF, improving hydration and barrier function. They also support protein synthesis, helping skin repair and maintain its structure. Amino acids are particularly beneficial for damaged or compromised skin barriers, as they provide the raw materials skin needs to rebuild.

Japanese skincare often features amino acid complexes in gentle cleansers and hydrating toners. Brands like Minon and Cow Brand focus on amino acid formulations for sensitive and dry skin. Amino acid surfactants are also popular in Japanese cleansers for their mildness.

How It Works

Replenishes natural moisturizing factors. Provides building blocks for protein synthesis. Supports barrier repair and hydration.

The Japanese Context

Popular in Japanese cleansers and toners for sensitive skin. Minon and Cow Brand specialize in amino acid formulations.

Best For

all skinsensitive skindry skin dehydration barrier damage sensitivity

How It's Used

Typical concentration: 1 to 10%, often as a blend of multiple amino acids

Ingredient Interactions

Side Effects and Cautions

Extremely well tolerated. Suitable for sensitive skin.

Products With Amino Acids